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ARA-290 vial, Diluent
Repair & Recovery

Buy ARA-290 UK

An 11-residue erythropoietin-derived peptide, as a 10mg vial. Research use only.

from £61.991 option

  • In stock Ships from the UK
  • Same-day dispatch Order before 2pm
  • Tracked delivery Free over £75
  • Certificate of analysis On request

ARA-290 is on the shelf at diluent.co.uk, held in British stock rather than ordered in, priced from £61.99 for the 10mg vial. It is supplied as vial. A weekday order placed before 2pm goes out the same day, tracked, boxed with nothing on the outside about the contents.

Shipping from inside the country is what removes the customs step: no clearance, no import charge, nothing sitting at a border. Purity is ≥99% by HPLC on every batch, and the certificate for the lot you are sent is yours on request against the number on the label.

Delivery runs £4.95, free above £75, tracked start to finish. See how ordering works.

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What is ARA-290?

Eleven amino acids taken from the Bα helix of erythropoietin, known as ARA-290 or cibinetide. What it does not bring with it is erythropoietin's effect on red cell production.

Specification

Residues11
Also listed asCibinetide
Derived fromThe Bα helix of erythropoietin
Purity≥99% by HPLC
Vial strength10mg
Vial stateLyophilised powder
CertificateOn request, against the batch number

What has ARA-290 been studied for?

The record behind ARA-290 is pre-clinical throughout. Not one of the papers listed below is a human trial. Below is what each paper set out to examine, sorted by the model it ran in:

Reviews of the literature

  • ARA 290 for treatment of small fiber neuropathy in sarcoidosis, Review (PMID 24555851)

Animal and in-vitro work

  • Cibinetide dampens innate immune cell functions thus ameliorating the course of experimental colitis, In-vitro study (PMID 29026145)

Other published work

  • ARA 290 relieves pathophysiological pain by targeting TRPV1 channel: Integration between immune system and nociception, Not stated in the record (PMID 26774587)

Each line describes what a paper looked at. None of it reports an effect in a person, and no part of this site tells anyone how to use anything.

Where and how to buy ARA-290 in the UK

How do you order?

Pick a strength from the table, put it in the basket and check out. There is no account to set up. The confirmation reaches you straight away and the payment details follow by email, because no card is taken on the site.

Why does UK stock matter?

The ARA-290 you order leaves a warehouse in Britain. That means no customs step, no import charge and no days lost in transit from abroad. Before 2pm on a working day and it is collected that afternoon, tracked, in an outer box that gives nothing away.

What arrives in the box?

Purity≥99%, by HPLC
LabellingCompound, strength, format, purity, research-use statement and a batch number
Certificate of analysisOn request, matched to your batch number
DeliveryTracked, UK only. £4.95, free over £75
Returns14 days on unopened, sealed items, terms

Reconstituting ARA-290

The vial arrives as a freeze-dried cake. It becomes a solution once bacteriostatic water goes in, and how much you add is what decides the strength of that solution. The quantity in the vial never changes, only the volume it is spread through.

5.00 mg/mlConcentration
0.100 mlHolds 0.5mg
10.0 unitsOn a U-100 syringe
50 mcgPer unit of that syringe

What you see here are concentrations and volumes. Nothing on this site is dosage, protocol or administration guidance, and no number above is one either.

Loaded with 10mg and 2ml to start. Move either control and the numbers move with it. The full reconstitution calculator goes further, into syringe units, which water to pick and how long a mixed vial lasts.

Concentration by vial size and water added
Vial+ 1ml+ 2ml+ 3ml+ 5ml
10mg 10 mg/ml5 mg/ml3.33 mg/ml2 mg/ml

Take the 10mg vial: 2ml of bacteriostatic water puts it at 5 mg/ml. The sum is the milligrams on the label over the millilitres you put in. Every figure here is a concentration. None of them is a dose, and this site carries no dosage, protocol or administration guidance at all.

How should it be handled?

  • Let a refrigerated vial reach room temperature first.
  • Wipe the stopper with an alcohol swab every time you go in.
  • Aim the water at the glass wall so it runs down, not straight onto the cake.
  • Roll it gently between your fingers. Shaking makes foam, and foam is damaged protein.
  • Give it a few minutes to go into solution. Done properly it finishes clear.

Storing ARA-290

Sealed vialSomewhere cool, dry and dark. For anything long term, the freezer.
Once reconstitutedFridge, standing upright, away from light. Never freeze it once mixed.

How long does it keep?

General figures for a lyophilised peptide
Stored asKeeps for
Sealed, frozen at −20 °CYears. Nothing holds a lyophilised peptide better than this
Sealed, refrigerated at 2–8 °CMonths
Sealed, at room temperatureWeeks. Fine while it is in the post, not a place to keep it
Reconstituted, refrigeratedThink weeks, not months. Four weeks is the number most people work to once bacteriostatic water is in, which is exactly what its preservative is there for
Reconstituted, frozenBest avoided. Ice crystals tear at peptides, and every freeze–thaw round makes it worse

Treat these as the usual numbers for lyophilised peptides, not a stability result measured on one batch. Cold and dry buys time; moisture, heat, light and being shaken about take it away. Ask and we will send the batch certificate of analysis.

We sell ARA-290 as an unlicensed research compound, for laboratory research use only. There is no UK marketing authorisation behind it, it is not a licensed medicine, and it is not for human use, veterinary use or food.

Nothing of this kind is a controlled drug, and selling it as laboratory material is lawful. Selling or marketing it for people to take is not. That line is the reason you will not find a dose, a protocol, a route, a frequency or a medical claim anywhere on this site, and the reason asking for one by email gets the same answer.

A few molecules in this range also appear inside a licensed medicine sold under a brand name. That authorisation belongs to the finished product it was granted for; it does not follow the molecule anywhere else. Full terms.

Research use only. Diluent supplies compounds for laboratory research. Nothing we sell is a licensed medicine, we are not a pharmacy, and we publish no dosage, protocol or administration guidance. Not for human or veterinary use, and not for use in food.

ARA-290 questions

What else is ARA-290 called?

Cibinetide is the non-proprietary name; ARA-290 was the development code it went through its trials under, which is why older indexing says ARA-290 and the newer papers say cibinetide. A third name, helix B surface peptide or HBSP, points at the stretch of erythropoietin the sequence came from. Four labels, one eleven-residue peptide.

What is it derived from?

The Bα helix of erythropoietin, minus the red-cell effect erythropoietin itself has.

Where can I buy ARA-290 in the UK?

ARA-290 is available in the UK from diluent.co.uk, from £61.99, a single 10mg size, as vials. The warehouse is in the UK, not overseas, which takes out the clearance wait, the handling fee and the chance of it being seized. That lands at £6.20 the milligram. It turns up as freeze-dried powder, so the concentration is yours to set when you mix it. Get the order in before 2pm on a weekday and it leaves that day, tracked, plainly packaged. Batches go to a third-party lab and come back at ≥99% by HPLC, and the certificate for yours is there if you ask, see how to order.

How much does ARA-290 cost?

It starts at £61.99 for the 10mg, £6.20 per mg. Postage runs £4.95, and nothing at all above £75.

How much bacteriostatic water do I add to ARA-290?

There is no single right answer, because the volume you choose is what fixes the strength. Take the 10mg vial: 1ml puts it at 10 mg/ml, 2ml at 5 mg/ml, 3ml at 3.33 mg/ml. The 10mg in the vial stays 10mg regardless. These are concentrations. They are not doses.

How should ARA-290 be stored?

Still sealed and dry it will sit for years at −20 °C, months in a fridge at 2–8 °C, weeks at room temperature. Cold and dry is what buys the time. After mixing it goes in the fridge standing up, and four weeks is the figure most work to with bacteriostatic water. Never freeze it once mixed: ice crystals tear peptides apart and each freeze–thaw round does it again.

What purity is your ARA-290, and can I see a certificate?

≥99%, measured by HPLC. Quote the batch number on your label and we will send the certificate of analysis for that lot. If you would rather see where current stock sits before you commit, ask and we will tell you.

References

  1. ARA 290 for treatment of small fiber neuropathy in sarcoidosis. Expert opinion on investigational drugs, 2014.. PMID 24555851
  2. Cibinetide dampens innate immune cell functions thus ameliorating the course of experimental colitis. Scientific reports, 2017.. PMID 29026145
  3. ARA 290 relieves pathophysiological pain by targeting TRPV1 channel: Integration between immune system and nociception. Peptides, 2016.. PMID 26774587

Each one links out so you can read the paper itself.