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MOTS-c vial, Diluent
Metabolic & GLP-1

Buy MOTS-c UK

A mitochondrial-derived peptide, in 5mg and 10mg vials. Research use only.

from £15.992 options

  • In stock Ships from the UK
  • Same-day dispatch Order before 2pm
  • Tracked delivery Free over £75
  • Certificate of analysis On request

MOTS-c is on the shelf at diluent.co.uk, held in British stock rather than ordered in, priced from £15.99 for the 5mg vial. It comes in 2 strengths, 5mg, 10mg, as vial. A weekday order placed before 2pm goes out the same day, tracked, boxed with nothing on the outside about the contents.

Shipping from inside the country is what removes the customs step: no clearance, no import charge, nothing sitting at a border. Purity is ≥99% by HPLC on every batch, and the certificate for the lot you are sent is yours on request against the number on the label.

Delivery runs £4.95, free above £75, tracked start to finish. See how ordering works.

Choose your MOTS-c

2 options
MOTS-c 5mg vial MOTS-c 5mg Vial · £3.20/mg
£15.99
MOTS-c 10mg vial MOTS-c 10mg Vial · £2.30/mg
£22.99

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What is MOTS-c?

Sixteen residues, and unusually its instructions live in the mitochondria: a short open reading frame inside the mitochondrial 12S rRNA. That places it in the group known as mitochondrial-derived peptides.

Specification

Residues16
Encoded byAn open reading frame in mitochondrial 12S rRNA
Molecular formulaC101H152N28O22S2
Molecular weight2,174.6
CAS1627580-64-6
Purity≥99% by HPLC
Vial strengths5mg, 10mg
CertificateOn request, against the batch number

What has MOTS-c been studied for?

The record behind MOTS-c is pre-clinical throughout. Not one of the papers listed below is a human trial. Below is what each paper set out to examine, sorted by the model it ran in:

Reviews of the literature

  • MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism, Review (PMID 27216708)

Animal and in-vitro work

  • The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance, Mouse and in-vitro (PMID 25738959)

Each line describes what a paper looked at. None of it reports an effect in a person, and no part of this site tells anyone how to use anything.

Where and how to buy MOTS-c in the UK

How do you order?

Pick a strength from the table, put it in the basket and check out. There is no account to set up. The confirmation reaches you straight away and the payment details follow by email, because no card is taken on the site.

Why does UK stock matter?

The MOTS-c you order leaves a warehouse in Britain. That means no customs step, no import charge and no days lost in transit from abroad. Before 2pm on a working day and it is collected that afternoon, tracked, in an outer box that gives nothing away.

What arrives in the box?

Purity≥99%, by HPLC
LabellingCompound, strength, format, purity, research-use statement and a batch number
Certificate of analysisOn request, matched to your batch number
DeliveryTracked, UK only. £4.95, free over £75
Returns14 days on unopened, sealed items, terms

Reconstituting MOTS-c

The vial arrives as a freeze-dried cake. It becomes a solution once bacteriostatic water goes in, and how much you add is what decides the strength of that solution. The quantity in the vial never changes, only the volume it is spread through.

2.50 mg/mlConcentration
0.100 mlHolds 0.25mg
10.0 unitsOn a U-100 syringe
25 mcgPer unit of that syringe

What you see here are concentrations and volumes. Nothing on this site is dosage, protocol or administration guidance, and no number above is one either.

Loaded with 5mg and 2ml to start. Move either control and the numbers move with it. The full reconstitution calculator goes further, into syringe units, which water to pick and how long a mixed vial lasts.

Concentration by vial size and water added
Vial+ 1ml+ 2ml+ 3ml+ 5ml
5mg 5 mg/ml2.5 mg/ml1.67 mg/ml1 mg/ml
10mg 10 mg/ml5 mg/ml3.33 mg/ml2 mg/ml

Take the 5mg vial: 2ml of bacteriostatic water puts it at 2.5 mg/ml. The sum is the milligrams on the label over the millilitres you put in. Every figure here is a concentration. None of them is a dose, and this site carries no dosage, protocol or administration guidance at all.

Asked about mixing MOTS-c

How long does MOTS-c last after reconstitution?

Let it warm to room temperature, wipe the stopper, then send the bacteriostatic water down the side of the glass instead of onto the powder. Roll it until it clears; never shake it. Concentration follows from the volume you picked, so on the 5mg vial, 1ml gives 5 mg/ml, 2ml gives 2.5 mg/ml, 3ml gives 1.67 mg/ml, 5ml gives 1 mg/ml.

How much bac water for 10mg MOTS-c?

Whatever volume goes in, the 10mg lands somewhere on this scale: 1ml gives 10 mg/ml, 2ml gives 5 mg/ml, 3ml gives 3.33 mg/ml, 5ml gives 2 mg/ml. We keep that size, so you will find it in the table above and as a choice in the picker.

How should it be handled?

  • Let a refrigerated vial reach room temperature first.
  • Wipe the stopper with an alcohol swab every time you go in.
  • Aim the water at the glass wall so it runs down, not straight onto the cake.
  • Roll it gently between your fingers. Shaking makes foam, and foam is damaged protein.
  • Give it a few minutes to go into solution. Done properly it finishes clear.

Storing MOTS-c

Sealed vialSomewhere cool, dry and dark. For anything long term, the freezer.
Once reconstitutedFridge, standing upright, away from light. Never freeze it once mixed.

How long does it keep?

General figures for a lyophilised peptide
Stored asKeeps for
Sealed, frozen at −20 °CYears. Nothing holds a lyophilised peptide better than this
Sealed, refrigerated at 2–8 °CMonths
Sealed, at room temperatureWeeks. Fine while it is in the post, not a place to keep it
Reconstituted, refrigeratedThink weeks, not months. Four weeks is the number most people work to once bacteriostatic water is in, which is exactly what its preservative is there for
Reconstituted, frozenBest avoided. Ice crystals tear at peptides, and every freeze–thaw round makes it worse

Treat these as the usual numbers for lyophilised peptides, not a stability result measured on one batch. Cold and dry buys time; moisture, heat, light and being shaken about take it away. Ask and we will send the batch certificate of analysis.

We sell MOTS-c as an unlicensed research compound, for laboratory research use only. There is no UK marketing authorisation behind it, it is not a licensed medicine, and it is not for human use, veterinary use or food.

Nothing of this kind is a controlled drug, and selling it as laboratory material is lawful. Selling or marketing it for people to take is not. That line is the reason you will not find a dose, a protocol, a route, a frequency or a medical claim anywhere on this site, and the reason asking for one by email gets the same answer.

A few molecules in this range also appear inside a licensed medicine sold under a brand name. That authorisation belongs to the finished product it was granted for; it does not follow the molecule anywhere else. Full terms.

Research use only. Diluent supplies compounds for laboratory research. Nothing we sell is a licensed medicine, we are not a pharmacy, and we publish no dosage, protocol or administration guidance. Not for human or veterinary use, and not for use in food.

MOTS-c questions

What is a mitochondrial-derived peptide?

One whose coding sequence sits in mitochondrial DNA instead of the nuclear genome. For MOTS-c that sequence is in the mitochondrial 12S rRNA.

What sizes do you stock?

Vials at 5mg and 10mg.

What is MOTS-c peptide?

We stock MOTS-c as an unlicensed research compound, sold for laboratory research and nothing else, assayed by HPLC at ≥99% purity. Its specification and the papers behind it are both further down this page.

Where can I buy MOTS-c peptide?

MOTS-c is available in the UK from diluent.co.uk, from £15.99, 2 strengths, 5mg to 10mg, as vials. The stock sits in Britain, so nothing waits on clearance, nothing attracts an import charge and nothing gets stopped on the way in. Buy bigger and the milligram gets cheaper: £2.30/mg at the keenest rate against £3.20/mg on the smallest vial, with every size carrying its own number. It turns up as freeze-dried powder, so the concentration is yours to set when you mix it. Get the order in before 2pm on a weekday and it leaves that day, tracked, plainly packaged. Batches go to a third-party lab and come back at ≥99% by HPLC, and the certificate for yours is there if you ask, see how to order.

How much does MOTS-c cost?

It starts at £15.99 for the 5mg, £3.20 per mg. 2 options in all, each with its own price and its own rate per milligram. Postage runs £4.95, and nothing at all above £75.

How long does MOTS-c last?

Still sealed and dry it will sit for years at −20 °C, months in a fridge at 2–8 °C, weeks at room temperature. Cold and dry is what buys the time. After mixing it goes in the fridge standing up, and four weeks is the figure most work to with bacteriostatic water. Never freeze it once mixed: ice crystals tear peptides apart and each freeze–thaw round does it again.

Is MOTS-c banned by wada?

We sell MOTS-c as an unlicensed research compound for laboratory research, and for nothing else. No UK marketing authorisation stands behind it, it is not a licensed medicine, and it is not for human or veterinary use. We are not a pharmacy.

What purity is your MOTS-c, and can I see a certificate?

≥99%, measured by HPLC. Quote the batch number on your label and we will send the certificate of analysis for that lot. If you would rather see where current stock sits before you commit, ask and we will tell you.

References

  1. The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance. Cell Metabolism, 2015;21(3):443-454. PMID 25738959
  2. MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism. PMID 27216708

Each one links out so you can read the paper itself.